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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a1b6c41a6e030a0b3d90f25096de2db983c1bd642838051c1d9bbdbb62f4021' 
  AND token = 'RvqCNnX/Q0USbRMRtxS6SYnMQGCrCfTRI9HXa996cjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}