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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd63301e5d6f21b3435e79a5c0897b1f859bdb502d77fe66e6219e384e613be50' 
  AND token = 'fCE1mU1Ms1tWwy7pNZKyz0S9qG6+Kd1WeHs9dCujHEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}