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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '436017f0e5a65c610db2ab90eeba2f5f105de77e35c70abb126ea1b50cd12f23' 
  AND token = 'dvnLG6ksP/6WgfdzPmFbBRDLI1LmtpKcsoUSSkZxFB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}