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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a81c7e4bf29175fcae7652270c2812b0b8b803ae169906121235a3e8cbc200d' 
  AND token = 'bP2jTvHRxEcizgZaX8afWqIZ7OLSx3q/jgA6IR80gPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}