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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ebc9735b3036c79c14a02f6a161ead370c67ab865bd4b77cfaf302391995082' 
  AND token = 'ANcoygqAWxLsR7mYc5qAlTsmfuCovHA1hA5Q1gYw0v0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}