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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc392fedf2b87fb919912a4008dfb1cc14d6d7ec21dd61c8e215473c41c0d235' 
  AND token = 'TOdtHLlY6amERnFMC+5Ch6iuBbBMTPfn6O+MFRgy56s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}