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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c370317ae5fbb90285d3d3c1c475eb165aaee0876e1c6e35b462b94a448ed49c' 
  AND token = '+U3qnUNqDdwGQO2z7xZAyQ6v9JX8V1c0F3OrzvoyxMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}