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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66c9556f4ca3bfc772f7c333bd23fb1d98a73f54c81ce8aafbe4741603dab588' 
  AND token = 'n8ekrxRyPDikyngtSQJE8Kx+HRlyJMyZPdqcEdpbHDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}