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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd05b1079dcb27c2232c4bef17ef65145ddf0e6392f83947c4072d4b1c4e0ba2' 
  AND token = 'Y436ZQBUAJb8mu5HrdgLbgrynLTYfBP65KKXvgxwcUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}