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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f522292a204f33507e0234b13099a05cbc9aae075ef57eba5251ed5de0a11298' 
  AND token = 'rs1c5Y4lI6OsLnrYGiyzj9pDse0Y5Yqt28q4JlkTZ3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}