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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b4151b6dc79bfa9e08b24c69cda77948fab06bc398f956b23ca22e9124398b5' 
  AND token = 'ngUGlaw6hb+AQxCjMrC3lN3Ga6ESm5PrQwew5aIg9Mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}