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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe1c990f924964a76b3182b8062ccf5bb597c1599293dce533f9d6ec14f6801c' 
  AND token = '24uc1/yi06PDQ39A/DUX2c2UHElyvNdtJ7N/lKLRYCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}