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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '853109214cd96bab64053fc8cd8ead4efcf8bdf0bea3933e9d8281a78f9e6e55' 
  AND token = 'PFQJPhAEZJU9vJPa9S1NM8ZxoHL4T4R+i+7XYh1rXyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}