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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa8eb84c40ca1c3ea4d8ecc9107f5efe863912538d31d81577f24a0072ff428f' 
  AND token = 'AfeWY4BrRGxM2jnkwDOCEuBo491zKVRm4TQ+BMeGvPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}