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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19c45e723609164f1602cb8118156f23850687ecbc32eaf80ad5d88d721a6f8f' 
  AND token = 'LjY2fYBeT6njk+g8Ci2ASgGSmb5KnEHxcl+rn1u9/8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}