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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4324c5c6280e252100d25bd9bab28ccf18a4c2a6cf4e053935f08b42d017d65' 
  AND token = 'qBjGJQyAXxPNoC9OFC6a2DRjFQggqgoprITEqUiqwNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}