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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c951437ab520122aec068a52a714a20a4cb784bc55a9aa5f20c87b59d499a0e' 
  AND token = '0BPTNE+1xgWaTlo39Mb/dv/f0nq42YHIs/6/EDA8SwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}