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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb7c7bcadead731bd406e53fdc40ddba87fca4f0bbfb03cf576a6b856572227' 
  AND token = 'FHnqrq2ltmBnBTJzFfMh6B+JRh3xca4Wyphhatj7hOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}