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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2e67def1ed7606cfd238e39ad7461ae1bd8aabb859729d9665697ba095f1332' 
  AND token = 'M6QaZ3bjDrSpTfQKwE6c6Ud/2V82KRTF19dWvCu6lbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}