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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b63c43654e3f51d6381c030fa82f787a2d6bc2f7c1d5ad9385382b4087c79db7' 
  AND token = 'ol8O9Pw4AiBN+9q6PwbC2Yw0VHFfcgoKklWetI5Si50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}