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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab40436d518c9a16738a5d2ec273e606b1389a053deef2cfae1adc4abffa7aa7' 
  AND token = 'DxfDlouef+e0DaHpIHkSWaN7Z+EFf3uLAGvgEYdTYZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}