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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c3a952eef27e39b839f137a165cd187d3dcbe59a83bafdf825822ed7b3c5e22' 
  AND token = '2LtqVytKi1vGjuZJCGcrTSv6b8QYaMnis+Xke34LKjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}