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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2e909b2459d12bf18730991e363cda5095b96fcec7f14f34b00c3a7e6cb8b19' 
  AND token = '6SGoMZnd9QIiC8p8vXzaUJPXcbmLzcTnCyY+TLXiC6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}