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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '426b133a49ab4b94e79306dbc0b396135a8a4ce67000c20846c89d34a168f579' 
  AND token = 'ZMsMqf17PdNNiocI9QGSSHTORnn4CwlsJvNPLK7s4mE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}