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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bc8bb25963a8664a53f7ee090f2dd743427516a726a12604401a4aea91fed56' 
  AND token = 'xlpj5kSRs5XSr1xkhJQ9pvT+nNlu5PzquL5dkaquKJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}