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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52450c88217c31ecb00d6eb5301aaf937854491d1eadc64439a3c24d34282f3a' 
  AND token = '93aessBXWgOQhGTEsE/Jvx/b4jY1JJ4Zo3PZJrs0swY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}