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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bb4e055d2d37fcd836546b9a2f06b1abd9e77c345b3d98047fe4fd56dd3dca7' 
  AND token = 'rdE9WbHCxvdAJpj5yOB3UUs32SafnxCFH4+eDR3+1AY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}