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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec3ae456e5036edd3cba321120d24de9e9cea9c2320fe39b46e1b01b2b66bfeb' 
  AND token = '7t/E059gBtZJFWwjBSTcFol+2XpPl23x2RPTj5Jp5f4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}