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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acb68f1188bc066b295a5d49bb48d4e6c3d347f99e9ecaaeb91969abbd373005' 
  AND token = 'o289Rdpto/rZAFOw264ButGR2CZs7qRCVXjohARecNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}