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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2722475de7e44e6d32ebcb55e3ca0424f9514a74dc77c55af73f220b965e1704' 
  AND token = 'W2ts20tQnMdeIAWPyR0uXTAFWm1zbKt1tlai6G8sJK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}