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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dcccdb4395fbade3357cd29eecd06cf714e77c32c769d22a226c1ec94f7b506' 
  AND token = 'X5Qsj7LMp4DecbEOHuKdI4REdsYT6BCo1jRF2ODwdrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}