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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f7696f03c081b022c47b458531722b5016f6468db76bbb689a4c4200a3faac2' 
  AND token = 'e3/rNqCovDBbWSRz7MBBbqGR8iHkb+0RS80qyxLzVt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}