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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22bc2cd2428e675727fd73f70afdb0e4285e6f956e755f934f863336f9f777a6' 
  AND token = 'PaLfx6wdQ1OiJoM1El2CSBSoYdf46abYNhQ02L/1yeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}