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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3db8a6e8304f1d39b38d5ad5f011302de41f566bd5b073f091b5405c259e78d2' 
  AND token = 'E5E82YYqCNFkhf9UBKESHyUczcZUamVmOx2/XXdWXoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}