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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db078bc8833ba3d622446cadbebb2c54a5d8e27a832b2ae7da9d74f139350160' 
  AND token = 'HaOY4dkrr8JPS02e7WNU93lF+ec0jwFPcxQECCwQL4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}