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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '453306f7b230839105b65751d8e54f56af2e8ed0ef31906e919eab8c57e6b966' 
  AND token = 'jY91SlrtpewXQqyjztIv2NaSdQdYAnPxpwwaWjnPs7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}