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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c0ddda41a418c213beb09e313f8ee832d57b0b9e908756e3807e80843c3afb2' 
  AND token = 'IsjMT9vTCwa75YK6JqFCDrLXRBS0fzQzpHDbLIgCpsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}