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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cadf768abc60b0d35f50682c07415d05449e9f5a6d5cf8a79e6ddb1b32c59f0' 
  AND token = 'que25HgPp8a1gpCcp1sH+npCYcrE64Csn86GM5mVjDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}