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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a988467b2f986b925937307b9d018bd5947fc29e18a6410d8d49b4c4c74b64e' 
  AND token = 'DlBmQG/c88Tj48xlOPUvf8lsFpVMEr+C67hTi/1NfQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}