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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdaae7b20abc95c1624908d297a02fc0ee8ccf7ef43deac11c21ce904a068e3f' 
  AND token = 'ZQGc6BS8mu3BB0uwcVlfejZ4En/Vhj+ta06dbUrzHP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}