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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a420a00c9d55c229d4716632424c212ce803ce90c00a5a2fdc6f4335251b70a' 
  AND token = 'ofG4ykOttc1g8EQAyx7dIUe7w+5JDY6BtRm9Gw9AcjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}