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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eef5b5fcd6b24125011dd62683efea993471363d81e6410f835c04d09385dcba' 
  AND token = '44gaC+W7Tog7+QWxGI7mjtr890raHvOxEYm/Vxk7Yck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}