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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '182808d4d723e63ebb381f2fa1eac0d366a32624868f6ad1b8e2aa5a370d2c47' 
  AND token = 'K8hHctC4mIDvFEtEtbdW+bemllPf5VNOHIYEnyuRtAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}