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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '262df14e7dde67cdbf2bc9a2201bfeb68f41a69b03041afdc03cc28689759769' 
  AND token = 'NPEOtgGACM1vJzl9umGV6J2EwOsFftYmJ0yNPK10PE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}