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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a14e02d24451e74d6958747bd10a5a7e0625fc069328bad4e6f07019dc56c14b' 
  AND token = '5iAk83zx/9HsL1c3HYi4aXOzR+nsIC29RrzOgo5U/4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}