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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6ad3c0a7a444c3b11038a67a0d38d55424e11a5acb1b083b2916f848e80a8c3' 
  AND token = '3Is7z0oSHm3LG0Byb2AIYxYuzrUxzB7BoBzUBiS341g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}