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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5342a9c7fa52e302e7dd794300584ec73ab317e2f838e4e056289109f0be837' 
  AND token = 'm9v8MXdT7jz9IaCu9KMDae+gcljslTENYARyAQlyq7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}