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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4cb551943c01e106f2bb027d1a64210f74a649620aed1fd18837c140c2d96d8' 
  AND token = 'Z3z08lCEPBx+bgHxLBgkCeVldOw3sml0snCgGAg8NW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}