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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89c16fb3ce1d0c0f014c37f5bd1d399dbde9c48d3cc0430b1eff3b238df82b59' 
  AND token = 'tUFOdi//V/R7EYAhycZUgtohfY9QG3616XVxgUdoqfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}