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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a3a210132423b36ef48ae9f1bdfaec7e837a7d320369e4b8c407c67d926911' 
  AND token = 'i85eTNWi5v2ke5l/OaK17eepz+l/I4lg9o4r5wesTf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}